NIH Small Business Innovation Research and Small Business Technology Transfer programs (America's Seed Fund powered by NIH)

NIH Small Business Innovation Research and Small Business Technology Transfer programs (America's Seed Fund powered by NIH) is a public funding body in the US. NIH's SBIR and STTR programmes give US for-profit small businesses non-dilutive grants for early-stage health and biomedical R&D. Phase I normally runs up to $323,090 and Phase II up to $2,153,927 in total funding, with higher amounts allowed for SBA-approved waiver topics. NIH funding opportunities were withdrawn during the 2025-26 lapse and released again on 29 May 2026.

What it offers

• “Phase I Total funding support (direct costs, indirect costs, fee) normally may not exceed $323,090” — ninds.nih.gov
• “Phase II Total funding support (direct costs, indirect costs, fee) normally may not exceed $2,153,927” — ninds.nih.gov
• “NIH has received a waiver from SBA to exceed the hard cap for specific topics; absolute funding restrictions are listed in the table.” — ninds.nih.gov
• “Small businesses and research organizations participating in NIA's SBIR and STTR programs retain intellectual property rights for their innovations.” — nia.nih.gov
• “Note: NOFO listings will include only the higher, ADRD-specific budget cap ($700,000 for Phase I and $3 million for Phase II).” — nia.nih.gov

Who can apply

• “Eligible businesses must be for-profit entities located in the United States” — nia.nih.gov
• “Eligible businesses must have 500 or fewer employees, including affiliates.” — nia.nih.gov
• “No single venture capital operating company, hedge fund, or private equity firm may own more than 50% of the concern.” — nia.nih.gov
• “The for-profit small business should conduct a minimum of 40% of the work, and a non-profit U.S. research institution should conduct a minimum of 30% of the work” — nia.nih.gov
• “Small businesses must complete required registrations before submitting an application, which can take six to eight weeks.” — ninds.nih.gov

How to apply

Apply or read the rules on the official site.

About this listing

TrustList compiled this listing from NIH Small Business Innovation Research and Small Business Technology Transfer programs (America's Seed Fund powered by NIH)'s official pages in September 2026. The quotes above are its own words. Amounts, deadlines and eligibility rules change, so check the official site before you rely on them.