Novo Ventures

We strive to invest in companies that develop innovative drugs, medical devices and diagnostics

We focus on generating strong financial returns from our portfolio of venture companies We invest in both private and public companies from an open evergreen fund This funding structure enables us to take a long-term perspective

With colleagues on the ground in Copenhagen, London, Singapore, San Francisco and Boston, we are well positioned in the major global life science hubs and can quickly respond to new and exciting investment opportunities wherever they emerge

We invest in biotechnology, medical technology and digital health companies Within biotech we primarily invest in companies with late preclinical or clinical stage compounds In medtech and digital health, we invest in commercial stage companies

We work actively with the companies we invest in by serving on the Boards of Directors Companies can also draw on our extensive network, as well as our commercial and scientific expertise within the life sciences

During 2021, Venture Investments executed 46 investments We deployed DKK 3 2 billion during the year Investment highlights include: • Verve Therapeutics, a gene editing company hoping to lower LDL cholesterol for familial hypercholesterolemia and one of the first in vivo gene editing therapies to begin clinical trials • Hummingbird Biosciences, a company using a systems biology approach to antibody discovery and development, and our first venture portfolio company with headquarters in Asia • Numab Therapeutics, a next generation antibody fragment platform company whose lead programme has the potential to become new standard of care in immune checkpoint therapy • Noom, a leading, high growth, global digital health platform

• Clever Care Health Plan
• Swift Health Systems / Inbrace Over the past 10 years
• 46 investments executed during 2021

investments executed during 2021

• 62 portfolio companies in 2021

portfolio companies in 2021

We are a focused team with streamlined decision making and we are quick to respond to investment opportunities when they arise

With professionals based out of Copenhagen, San Francisco, Boston and London and an international network of commercial and scientific specialists, our team is geared to invest in the major life science hubs

Novo Ventures (US) Inc * 501 2nd Street, Suite 300 San Francisco, CA 94107 USA +1 (415) 552-6686 Novo Ventures (US) Inc * 200 Clarendon Street, Floor 45 Boston, MA 02116 USA Novo Ventures (UK) 16 Berkeley Street Mayfair, London W1J 8NR UK

• Novo Ventures (US) Inc is a separate legal entity that provides certain consultancy services to Novo Holdings A/S, mainly within the areas of identifying, analysing and negotiating various investment opportunities among life science and biotech companies in the US as well as certain follow-up activities related thereto, such as board memberships, financial control and reporting efforts