Downing Ventures

• as at August 2022 Healthcare systems worldwide are facing significant headwinds – ageing populations with long-term chronic care needs are creating relentless pressure on systems which are also struggling with the post-Covid legacy, workforce challenges and accelerating costs These long-term trends are creating opportunities for new, tech-enabled and evidence-based solutions to change the paradigm of care Our focus will be on companies operating at this intersection of healthcare with technology where solutions that improve access and outcomes whilst reducing costs can be implemented to the benefit of both the provider and the patient

Access to a specialist team Investments will be managed by a team of healthcare experts led by Dr Nigel Pitchford who has a 25-year track record of healthcare ventures investment across a range of firms The team possesses exceptional investment expertise but also operational experience too, meaning they have a deeper understanding of the challenges facing early stage healthtech companies and how to solve them

As well as the prospect of capital growth and diversification, there’s another reason to consider adding healthcare investments to your portfolio: making a positive impact This can include: More personalised care, leading to better patient outcomes Connecting more people to healthcare solutions, leading to greater coverage and quicker diagnosis Better treatments and devices, saving and extending more lives

Downing’s approach to impact investing is to back companies that contribute to the United Nations Sustainable Development Goals (SDGs) while delivering returns for investors The UK has world-leading education and research institutions that contribute to its status as a global healthcare & life sciences hub This environment fosters growth and innovation, and we believe the early-stage, UK-based companies within this sector contribute to the core objective of SDG3: Good Health and Well-being – “To ensure healthy lives and promote well-being for all at all ages ” Open Bionics: Turning disabilities into superpowers Future Health Works: Meeting the complex needs of orthopaedic patients Fundamental VR: Developing the next-generation flight simulator for surgeons Downing LLP makes another senior hire in its Healthcare Ventures team to support future fundraising plans Cydar Medical – minimal invasion, maximum precision 2023 healthcare ventures outlook: How the rise of ‘healthtech’ is transforming our healthcare experience If you would like to find out more about the Healthcare Ventures team, please click the link below

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Downing LLP does not provide advice or make personal recommendations and investors are strongly urged to seek independent advice before investing Investments offered on this website carry a higher risk than many other types of investment and prospective investors should be aware that capital is at risk and the value of their investment may go down as well as up Any investment should only be made on the basis of the relevant product literature and your attention is drawn to the risk, fees and taxation factors contained therein Tax treatment depends on individual circumstances of each investor and may be subject to change in the future Past performance is not a reliable indicator of future performance Downing LLP is authorised and regulated by the Financial Conduct Authority (Firm Reference Number 545025) Registered in England No OC341575 Registered Office: St Magnus House, 3 Lower Thames Street, London EC3R 6HD

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