Boulder Ventures

Boulder Ventures I - VII:

Mineralys Therapeutics has penciled in a $100 million initial public offering to take its investigational hypertension drug into Phase III testing

The Philadelphia startup released topline results for its hypertension drug, dubbed MLS-101 or lorundrostat, two months ago, saying it met the primary endpoint of reducing systolic blood pressure for patients who were on at least two background medicines

LOVELAND, Colo , Jan 3, 2023 /PRNewswire/ -- Heska Corporation (NASDAQ: HSKA; "Heska" or the "Company"), a leading global provider of advanced veterinary diagnostic and specialty products and solutions, today announced the completion of acquisition of 100% of the shares of MBio Diagnostics, Inc d/b/a LightDeck Diagnostics ("LightDeck"), a pioneer in planar waveguide fluorescence immunoassay diagnostics with strong manufacturing capabilities and research and development expertise (the "Acquisition")

Mike Arnold grew up ski racing in Maine, discovered backcountry in Colorado and now works as a professional mountain guide in Italy’s Aosta Valley Surrounded by 4,000-metre alpine peaks, his adopted home is the historical home of ski mountaineering In this tight-knit local community, guides have always been highly respected But they face high risks, too

Having gained so much from the mountains, Mike has recently been forced to come to terms with what they can take away He is paid to do what he loves but is it worth the risk? I have been investing in startups since 1985, and guiding since 1976 After 60 portfolio company investments from 11 different venture funds that I’ve managed, and after guiding hundreds of clients in the mountains of Colorado, Canada, and Europe over the past 40 years on skis and on rock, I’ve come to this conclusion

I’ve spent my career as a venture capitalist trying to figure out how to get a higher hit rate from the investments we make You only get a dozen or so deals in a small fund like ours, and we’re actively involved in each one

We guide our clients on good days and bad, sometimes to the top, sometimes not We learn every time we succeed and every time we fail, but most importantly, we always return to climb again

In mountain guiding and in venture capital, durability is the key to success

We’ve learned a lot from the CMH guides over our years together in the field, and one of them is to disseminate information about mistakes throughout our organization and portfolio companies That way, when we do make mistakes, they are Original Mistakes, not the same ones other people have already made

Kyle Lefkoff on the North Face of K2 (1986) 1941 Pearl Street, #300 Boulder, CO 80302 Phone: 303-444-6950 5425 Wisconsin Avenue, Suite 704 Chevy Chase, MD  20815 Phone:  301-913-0213